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Bacteriophage Bionanowire as a Carrier for Both Cancer‐Targeting Peptides and Photosensitizers and its use in Selective Cancer Cell Killing by Photodynamic Therapy
Author(s) -
Gandra Naveen,
Abbineni Gopal,
Qu Xuewei,
Huai Yanyan,
Wang Li,
Mao Chuanbin
Publication year - 2013
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.201202090
Subject(s) - library science , chemistry , gerontology , medicine , computer science
A photosensitizer, pyropheophorbid‐a (PPa) , is conjugated to SKBR‐3 breast cancer cell‐specific biological nanowire phage, to form a novel PPa‐phage complex, which is further successfully used in selectively killing SKBR‐3 breast cancer cells by the mechanism of photodynamic therapy (PDT).