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Artificial Cytoskeletal Structures Within Enzymatically Active Bio‐inorganic Protocells
Author(s) -
Kumar Ravinash Krishna,
Li Mei,
Olof Sam N.,
Patil Avinash J.,
Mann Stephen
Publication year - 2013
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.201201539
Subject(s) - protocell , supramolecular chemistry , dephosphorylation , nanotechnology , cytoskeleton , computer science , artificial cell , chemistry , materials science , molecule , biochemistry , enzyme , cell , organic chemistry , membrane , phosphatase
The fabrication of enzymatically active, semi‐permeable bio‐inorganic protocells capable of self‐assembling a cytoskeletal‐like interior and undergoing small‐molecule dephosphorylation reactions is described. Reversible disassembly of an amino acid‐derived supramolecular hydrogel within the internalized reaction space is used to tune the enzymatic activity of the nanoparticle‐bounded inorganic compartments.