Tunable Biomolecular Interaction and Fluorescence Quenching Ability of Graphene Oxide: Application to “Turn‐on” DNA Sensing in Biological Media | Zendy

Hong Bong Jin | Zendy; An Zhi | Zendy; Compton Owen C. | Zendy; Nguyen SonBinh T. | Zendy

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Tunable Biomolecular Interaction and Fluorescence Quenching Ability of Graphene Oxide: Application to “Turn‐on” DNA Sensing in Biological Media

Author(s) -

Hong Bong Jin,

An Zhi,

Compton Owen C.,

Nguyen SonBinh T.

Publication year - 2012

Publication title -

small

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.785

H-Index - 236

eISSN - 1613-6829

pISSN - 1613-6810

DOI - 10.1002/smll.201200264

Subject(s) - graphene , quenching (fluorescence) , oxide , fluorescence , dna , turn (biochemistry) , materials science , nanotechnology , photochemistry , biophysics , chemistry , biochemistry , physics , optics , biology , metallurgy

As a platform for “turn‐on” DNA sensing , the level of oxidation of graphene oxide strongly affects its fluorescence quenching ability and binding interactions to single‐stranded oligodeoxyribonucleotides (ssODNs), leading to a broad range of sensitivity. Fine‐tuning the level of oxidation of graphene oxide yields a DNA‐detection platform that is highly sensitive in serum and biological media.

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