Premium
Drug Delivery: Vaults Engineered for Hydrophobic Drug Delivery (Small 10/2011)
Author(s) -
Buehler Daniel C.,
Toso Daniel B.,
Kickhoefer Valerie A.,
Zhou Z. Hong,
Rome Leonard H.
Publication year - 2011
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.201190037
Subject(s) - drug delivery , vault (architecture) , drug , nanotechnology , materials science , targeted drug delivery , biomedical engineering , medicine , engineering , pharmacology , structural engineering
The frontispiece of the Full Papers section (right) shows a single‐particle electron microscope tomography reconstruction, which reveals that a fully assembled drug‐loaded nanodisk (red) can be packaged into the vault lumen (green) as a viable method for vault‐mediated drug delivery. The electron micrograph in the background shows negatively stained vaults containing nanodisks. For more information, please read the Full Paper “Vaults Engineered for Hydrophobic Drug Delivery” by L. H. Rome and co‐workers, beginning on page 1431 .