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Entrapment of Protein in Nanotubes Formed by a Nanochannel and Ion‐Channel Hybrid Structure of Anodic Alumina
Author(s) -
Chen Wei,
Jin Bo,
Hu YuLin,
Lu Yu,
Xia XingHua
Publication year - 2012
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.201102117
Subject(s) - nanopore , electromigration , anode , materials science , trapping , layer (electronics) , nanotechnology , nanofluidics , ion , barrier layer , porosity , ion channel , chemical engineering , chemistry , composite material , organic chemistry , electrode , ecology , engineering , biology , biochemistry , receptor
The nanochannel (in a porous layer) and ion‐channel (in a barrier layer) hybrid structure of anodic alumina is used as a protein‐trapping device. The transmembrane potential drives the electromigration of the charged proteins (FITC‐labeled) into the nanochannels, but electromigration across the barrier layer is impossible due to the size‐exclusion effect. As a result, the proteins can be continuously trapped in the nanochannels.