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Conjugated Polymers for Light‐Activated Antifungal Activity
Author(s) -
Xing Chengfen,
Yang Gaomai,
Liu Libing,
Yang Qiong,
Lv Fengting,
Wang Shu
Publication year - 2012
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.201101825
Subject(s) - polythiophene , photoexcitation , cationic polymerization , singlet oxygen , porphyrin , conjugated system , polymer , photochemistry , materials science , antifungal , chemistry , polymer chemistry , conductive polymer , oxygen , organic chemistry , excited state , medicine , physics , dermatology , nuclear physics
A cationic polythiophene−porphyrin (PTP) dyad is shown to exhibit efficient light‐activated antifungal activity. Higher singlet oxygen ( 1 O 2 ) generation efficiency can be attained from PTP upon photoexcitation due to the light‐harvesting properties of the polymer backbone and efficient energy transfer from the polythiophene to the porphyrin units. PTP can be used for treating fungal infections in lower doses of irradiation light and polymer concentration.