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Enrichment and Detection of Peptides from Biological Systems Using Designed Periodic Mesoporous Organosilica Microspheres
Author(s) -
Qian Kun,
Gu Wenyi,
Yuan Pei,
Liu Fang,
Wang Yunhua,
Monteiro Michael,
Yu Chengzhong
Publication year - 2012
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.201101770
Subject(s) - microsphere , mesoporous material , mesoporous organosilica , nanotechnology , materials science , computer science , chemical engineering , chemistry , organic chemistry , mesoporous silica , catalysis , engineering
Periodic mesoporous organosilica microspheres (PMOMs) are designed with integrated structural features, including a cubic mesostructure, hydrophobic wall composition, a uniform pore size of ≈3 nm, and a spherical morphology in micrometers, all advantageous for size‐selective and highly efficient enrichment of peptides from mixtures. Consequently, PMOMs can be used to capture peptides in a range of complex biological systems.