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Correlation of the Cytotoxicity of TiO 2 Nanoparticles with Different Particle Sizes on a Sub‐200‐nm Scale
Author(s) -
Cai Kaiyong,
Hou Yanhua,
Hu Yan,
Zhao Li,
Luo Zhong,
Shi Yisong,
Lai Min,
Yang Weihu,
Liu Peng
Publication year - 2011
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.201101170
Subject(s) - cytotoxicity , nanoparticle , nanoscopic scale , particle size , nanotechnology , nanomaterials , particle (ecology) , scale (ratio) , materials science , chemistry , physics , biochemistry , in vitro , biology , quantum mechanics , ecology
The size‐mediated cytotoxicity of TiO 2 nanoparticles is investigated at the cellular and molecular levels. The cytotoxicity dramatically increases around a particle size of 100 nm (nanoscale effect). This finding affords new insights into the cytotoxicity of nanomaterials, and has potential implications in the design of nanostructured biomaterials.