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Using Charge to Control the Functional Properties of Self‐Assembled Nanopores in Membranes
Author(s) -
Macrae Michael X.,
Schlamadinger Diana,
Kim Judy E.,
Mayer Michael,
Yang Jerry
Publication year - 2011
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.201100394
Subject(s) - conductance , nanopore , channel (broadcasting) , membrane , spiropyran , charge (physics) , ion channel , ion , nanotechnology , covalent bond , gramicidin , materials science , chemistry , computer science , physics , photochromism , telecommunications , organic chemistry , biochemistry , receptor , condensed matter physics , quantum mechanics
Light sensitive, semisynthetic ion channels allow for the modulation of multiple channel properties. Covalent attachment of a photoswitchable spiropyran group to the entrance of a gramicidin A ion channel enables reversible control of both conductance and channel lifetime, which show opposite trends in behavior at high and low salt concentrations.