Premium
Electrochemically Controlled Deconjugation and Delivery of Single Quantum Dots into the Nucleus of Living Cells
Author(s) -
Yum Kyungsuk,
Wang Ning,
Yu MinFeng
Publication year - 2010
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.201000855
Subject(s) - nanoneedle , nucleus , quantum dot , nanotechnology , living cell , electrochemistry , cell membrane , biophysics , cell , materials science , chemistry , electrode , nanostructure , neuroscience , biology , microbiology and biotechnology , biochemistry
A membrane‐penetrating nanoneedle (also serving as a nanoelectrode) is developed for carrying and rapidly releasing individual quantum dots into the nucleus of a living cell via an electrochemical reaction activated by an electrical pulse. Direct delivery of biological probes into the nucleus with high spatial and temporal precision offers new strategies for the study of biological activity in a living cell.