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Uniform Beads with Controllable Pore Sizes for Biomedical Applications
Author(s) -
Choi SungWook,
Yeh YiChun,
Zhang Yu,
Sung HsingWen,
Xia Younan
Publication year - 2010
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.201000544
Subject(s) - materials science , fluidics , nanotechnology , microfluidics , drug delivery , engineering , aerospace engineering
Uniform beads of poly( D,L ‐lactide‐ co ‐ glycolide) with small or large pores are fabricated by selectively introducing phase‐separated layers of an unstable emulsion into a fluidic device using a syringe with a tip offset from the barrel. When fibroblasts are cultured in the beads, a higher density of viable cells occurs in the beads with larger pores. These beads could be useful for tissue engineering and cell‐delivery applications.