Aptatag‐Based Multiplexed Assay for Protein Detection by Surface‐Enhanced Raman Spectroscopy | Zendy

Fabris Laura | Zendy; Schierhorn Martin | Zendy; Moskovits Martin | Zendy; Bazan Guillermo C. | Zendy

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Aptatag‐Based Multiplexed Assay for Protein Detection by Surface‐Enhanced Raman Spectroscopy

Author(s) -

Fabris Laura,

Schierhorn Martin,

Moskovits Martin,

Bazan Guillermo C.

Publication year - 2010

Publication title -

small

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.785

H-Index - 236

eISSN - 1613-6829

pISSN - 1613-6810

DOI - 10.1002/smll.201000262

Subject(s) - aptamer , polyethylene glycol , raman spectroscopy , surface enhanced raman spectroscopy , multiplexing , selectivity , protein detection , materials science , nanoparticle , dna , colloidal gold , bioassay , nanotechnology , chemistry , chromatography , microbiology and biotechnology , raman scattering , biochemistry , optics , biology , physics , electrical engineering , genetics , engineering , catalysis

Silver‐nanoparticle dimers held together by a Raman reporter, capped with DNA aptamers and stabilized by polyethylene glycol chains, can be used to develop a multiplexed heterogeneous bioassay for protein detection with high sensitivity and selectivity.

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