Premium
Microfluidic Rheometer for Characterization of Protein Unfolding and Aggregation in Microflows
Author(s) -
Choi Sungyoung,
Park JeKyun
Publication year - 2010
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.201000210
Subject(s) - rheometer , rheology , microfluidics , materials science , viscosity , pressure drop , denaturation (fissile materials) , characterization (materials science) , chemistry , chemical engineering , nanotechnology , thermodynamics , composite material , engineering , physics , nuclear chemistry
The balance between a sample and reference flow with a common pressure drop enables simple and accurate measurement of fluid viscosity without standard pressure gauges and complicate theoretical calculations. The microfluidic rheometer measures minute changes in a rheological property of bovine serum albumin by chemical and thermal denaturation.