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Radiation‐Luminescence‐Excited Quantum Dots for in vivo Multiplexed Optical Imaging
Author(s) -
Liu Hongguang,
Zhang Xiaofen,
Xing Bengang,
Han Peizhen,
Gambhir Sanjiv Sam,
Cheng Zhen
Publication year - 2010
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.200902408
Subject(s) - quantum dot , luminescence , excited state , fluorescence , radiation , materials science , preclinical imaging , optoelectronics , optical imaging , fluorescence lifetime imaging microscopy , in vivo , nanotechnology , optics , physics , atomic physics , microbiology and biotechnology , biology
A new method to illuminate quantum dots (QDs) by radiation luminescence as an internal light source is reported. The excited QDs can produce fluorescence for both in vitro and in vivo imaging. This study provides an alternate strategy for the design of self‐illuminated optical imaging agents. Radiation‐luminescence‐excited QDs can also be readily adapted for dual‐modality imaging.