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Cowpea Mosaic Virus Unmodified Empty Viruslike Particles Loaded with Metal and Metal Oxide
Author(s) -
Aljabali Alaa A. A.,
Sainsbury Frank,
Lomonossoff George P.,
Evans David J.
Publication year - 2010
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.200902135
Subject(s) - cowpea mosaic virus , capsid , nanotechnology , metal , oxide , mosaic , virology , virus , chemistry , plant virus , materials science , computer science , biology , geography , organic chemistry , archaeology
Empty (devoid of RNA) viruslike particles (eVLPs) of Cowpea mosaic virus can now be obtained readily. CPMV can encapsulate, within the protein capsid, cobalt or iron oxide by environmentally benign processes. The external surface also remains amenable to chemical modification. The development of eVLPs for targeted delivery of therapeutic agents is now a reality.