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In vitro Capture, Transport, and Detection of Protein Analytes Using Kinesin‐Based Nanoharvesters
Author(s) -
CarrollPortillo Amanda,
Bachand Marlene,
Greene Adrienne C.,
Bachand George D.
Publication year - 2009
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.200900491
Subject(s) - kinesin , analyte , electrokinetic phenomena , nanotechnology , microfluidics , motor protein , quantum dot , computer science , chemistry , materials science , chromatography , biology , microtubule , microbiology and biotechnology
Kinesin biomolecular motors and quantum dots (QDs) are used to capture, transport, and detect target protein analytes (see image). Nanoharvesters (QDs + kinesin + antibodies) provide a novel means for performing microfluidic diagnostic assays that do not rely on mechanical pumping or electrokinetic flow of analytes.