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Preparation of Phospholipid Multilayer Patterns of Controlled Size and Thickness by Capillary Assembly on a Microstructured Substrate
Author(s) -
Diguet Antoine,
Le Berre Maël,
Chen Yong,
Baigl Damien
Publication year - 2009
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.200900368
Subject(s) - phospholipid , materials science , substrate (aquarium) , capillary action , silicon , liposome , chemical engineering , nanotechnology , membrane , composite material , chemistry , optoelectronics , biochemistry , oceanography , engineering , geology
By dragging a phospholipid solution on microstructured silicon surfaces, phospholipid molecules are selectively deposited inside the microstructures to get regular phospholipid multilayer patterns of controlled thickness over a large scale (∼cm 2 ). By varying the dragging speed, the thickness of the patterns varies between 28 and 100 nm on average (7 to 25 bilayers). Electroswelling of phospholipid multilayer patterns leads to the formation of giant liposomes of controlled size and narrow size distributions.