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Mechanism for a Directional, Processive, and Reversible DNA Motor
Author(s) -
Bath Jonathan,
Green Simon J.,
Allen Katherine E.,
Turberfield Andrew J.
Publication year - 2009
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.200900078
Subject(s) - directionality , dna , mechanism (biology) , molecular motor , atp hydrolysis , nanotechnology , materials science , biophysics , chemistry , physics , biochemistry , genetics , biology , enzyme , atpase , quantum mechanics
Two left feet? Directionality is established in a processive DNA motor by coordinating the reactivities of two identical feet (see picture). Energy is provided by hydrolysis of a single‐stranded DNA fuel. The directional bias of the motor can be controlled through the choice of fuel.