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Facile Preparation of Monodisperse Pharmaceutical Colloidal Spheres of Atorvastatin Calcium via Self‐Assembly
Author(s) -
Zhang HaiXia,
Zhao Hong,
Wang JieXin,
Chen JianFeng,
Lu YunFeng,
Yun Jimmy
Publication year - 2009
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.200900018
Subject(s) - dispersity , materials science , nanotechnology , drug delivery , nanoparticle , self assembly , chemical engineering , drug carrier , colloid , polymer chemistry , engineering
Colloidal spheres of atorvastatin calcium (see picture) with tunable size and enhanced dissolution rate are obtained by a solvation‐driven molecular assembly method. This technique enables the large‐scale synthesis of monodisperse pharmaceutical spheres, to facilitate their delivery and maximize their therapeutic effectiveness.