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The Biocompatibility of Apoferritin‐Encapsulated PbS Quantum Dots
Author(s) -
Turyanska Lyudmila,
Bradshaw Tracey D.,
Sharpe Jason,
Li Mei,
Mann Stephen,
Thomas Neil R.,
Patanè Amalia
Publication year - 2009
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.200900017
Subject(s) - quantum dot , biocompatibility , materials science , nanotechnology , cytotoxicity , chemistry , in vitro , biochemistry , metallurgy
A PbS quantum dot encapsulated into the hollow core of an apoferritin protein (see image) offers several advantages over existing composites based on quantum dots including a lower level of cytotoxicity, differential toxicity between healthy and cancerous cells, emission tunable in the near‐infrared wavelength range of interest for bioimaging, water solubility and stability, and the same mobility as that of apoferritin.