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Individual Blood‐Cell Capture and 2D Organization on Microarrays
Author(s) -
Roupioz Yoann,
BerthetDuroure Nathalie,
Leïchlé Thierry,
Pourciel JeanBernard,
Mailley Pascal,
Cortes Sandra,
Villiers MarieBernadette,
Marche Patrice N.,
Livache Thierry,
Nicu Liviu
Publication year - 2009
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.200801941
Subject(s) - biochip , nanotechnology , dna microarray , computer science , materials science , information retrieval , computational biology , biology , gene , genetics , gene expression
Individual cell addressing on an arrayed biochip is achieved. Gold layers are electrochemically functionalized by arraying antibodies using silicon‐made microcantilevers (see image). Because the spot size is close to a lymphocyte diameter, living blood cells are successfully bound and organized on the surfaces according to the micrometric features.