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Nanopatterning Peptides as Bifunctional Inks for Templated Assembly
Author(s) -
Wei Joseph H.,
Kacar Turgay,
Tamerler Candan,
Sarikaya Mehmet,
Ginger David S.
Publication year - 2009
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.200801911
Subject(s) - bifunctional , streptavidin , nanotechnology , biotinylation , dip pen nanolithography , nanolithography , chemistry , self assembly , phage display , computer science , materials science , combinatorial chemistry , peptide , biochemistry , biotin , fabrication , catalysis , medicine , alternative medicine , pathology
Peptides selected via cell‐surface or phage display for their ability to bind inorganic surfaces can be used as inks in dip‐pen nanolithography with sub‐100‐nm resolution (see image). Two different biotinylated peptides are chosen because they exhibit preferential binding to either gold or silica surfaces and can be used as bifunctional linkers to direct the site‐specific assembly of fluorescently‐labeled streptavidin.