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Electrophysiological Study of Single Gold Nanoparticle/ α ‐Hemolysin Complex Formation: A Nanotool to Slow Down ssDNA Through the α ‐Hemolysin Nanopore
Author(s) -
Astier Yann,
Uzun Oktay,
Stellacci Francesco
Publication year - 2009
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.200801779
Subject(s) - nanopore , nanoparticle , nanotechnology , materials science , colloidal gold , monolayer , conductance , hemolysin , surface charge , chemistry , physics , biochemistry , condensed matter physics , virulence , gene
Single‐monolayer‐protected gold nanoparticles can be captured in the α‐hemolysin nanopore (see image). Single‐nanopore ion conductance studies of the nanoparticle/nanopore complex are described. The effect of the nanoparticle size, charge, and surface coating on ssDNA threading speed through the nanopore/nanoparticle complex is discussed.