Premium
Micro‐Nanostructured Protein Arrays: A Tool for Geometrically Controlled Ligand Presentation
Author(s) -
Aydin Daniel,
Schwieder Marco,
Louban Ilia,
Knoppe Stefan,
Ulmer Jens,
Haas Tobias L.,
Walczak Henning,
Spatz Joachim P.
Publication year - 2009
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.200801219
Subject(s) - nanotechnology , template , fabrication , colloidal gold , materials science , nanoparticle , micrometer , ligand (biochemistry) , presentation (obstetrics) , deposition (geology) , chemistry , optics , biology , physics , paleontology , sediment , radiology , medicine , biochemistry , alternative medicine , receptor , pathology
A novel approach for the rapid fabrication of extended areas of micrometer‐scaled patches of quasi‐hexagonally ordered gold nanoparticle arrays (see image) is presented. The resulting substrates serve as templates for the site‐specific immobilization of proteins to gold nanoparticles enabling nanoscopically and microscopically controlled protein deposition.