Repairing the Damaged Spinal Cord and Brain with Nanomedicine | Zendy

Cho Youngnam | Zendy; Shi Riyi | Zendy; Borgens Richard | Zendy; Ivanisevic Albena | Zendy

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Repairing the Damaged Spinal Cord and Brain with Nanomedicine

Author(s) -

Cho Youngnam,

Shi Riyi,

Borgens Richard,

Ivanisevic Albena

Publication year - 2008

Publication title -

small

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.785

H-Index - 236

eISSN - 1613-6829

pISSN - 1613-6810

DOI - 10.1002/smll.200800838

Subject(s) - spinal cord , spinal cord injury , peg ratio , polyethylene glycol , ex vivo , nanomedicine , in vivo , medicine , anatomy , materials science , chemistry , biology , nanotechnology , nanoparticle , biochemistry , microbiology and biotechnology , finance , psychiatry , economics

Polyethylene glycol (PEG)‐coated silica colloids circulating in the bloodstream target only injured tissues, particularly a spinal‐cord injury (see picture). The PEG coating both seals and induces repair of damaged cells, leading to a recovery of physiological function. These PEG‐coated colloids have been characterized, tested in ex vivo spinal cord and in living adult Guinea pig spinal‐cord injury.

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