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Direct‐Write Nanoparticle Microarrays for Cell Assays
Author(s) -
Jang KyungJin,
Nam JwaMin
Publication year - 2008
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.200800270
Subject(s) - ethylene glycol , nanoparticle , dna microarray , nanotechnology , materials science , cell growth , cell , biochip , microarray , chip , chemistry , computer science , gene expression , biochemistry , gene , telecommunications , organic chemistry
A simple and straightforward method for creating nanoparticle microarrays on poly(ethylene glycol) brushes by using a noncontact microarrayer provides cellular nanoenvironment platforms for high‐throughput and high‐content cell assays on a single chip. Better transfection efficiency, cell proliferation, and cell survival are observed when cells are assayed on the nanofeatured surface (see image) than when they were assayed on a flat glass surface without nanofeatures.