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Metallic Iron Nanoparticles for MRI Contrast Enhancement and Local Hyperthermia
Author(s) -
Hadjipanayis Costas G.,
Bonder Michael J.,
Balakrishnan Srinivasan,
Wang Xiaoxia,
Mao Hui,
Hadjipanayis George C.
Publication year - 2008
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.200800261
Subject(s) - atlanta , library science , medicine , management , pathology , computer science , metropolitan area , economics
New metallic magnetic nanoparticles with greater magnetic properties than current iron oxide nanoparticles (IONPs) of comparable size (10 nm) are described. The multifunctional iron‐based NPs coated with biocompatible carboxyl‐terminated polyethylene glycol (see image) generate more effective local hyperthermia when subjected to an oscillating magnetic field and have a stronger MRI T 2 shortening effect than IONPs.