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3C–SiC Nanocrystals as Fluorescent Biological Labels
Author(s) -
Fan Jiyang,
Li Hongxia,
Jiang Jiang,
So Leo K. Y.,
Lam Yun Wah,
Chu Paul K.
Publication year - 2008
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.200800080
Subject(s) - photobleaching , fluorescence , nanocrystal , cytotoxicity , materials science , inert , nanotechnology , silicon carbide , nanoparticle , internalization , biophysics , chemistry , cell , in vitro , organic chemistry , biochemistry , biology , metallurgy , physics , quantum mechanics
Silicon carbide nanocrystals are water‐soluble, chemically inert, and highly fluorescent, and they may be idealas biological labels. After the uptake of3C–SiC nanocrystals, human fetal osteoblast (hFOB) cells exhibit brightgreen–yellow fluorescence (see image).The nanoparticles show high resistanceagainst photobleaching with no significant cytotoxicity.