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Supramolecular Interactions at the Picomole Level Studied by 19 F NMR Spectroscopy in a Microfluidic Chip
Author(s) -
Gómez M. Victoria,
Reinhoudt David N.,
Velders Aldrik H.
Publication year - 2008
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.200701306
Subject(s) - microcoil , supramolecular chemistry , microfluidics , nuclear magnetic resonance spectroscopy , spectroscopy , materials science , chip , resolution (logic) , analytical chemistry (journal) , nanotechnology , chemistry , molecule , chromatography , stereochemistry , organic chemistry , computer science , telecommunications , physics , quantum mechanics , artificial intelligence , electrical engineering , electromagnetic coil , engineering
Small‐scale chips : 19 F NMR spectroscopy is performed on nanoliter volumes in a microfluidic chip equipped with a planar microcoil (see picture). The high resolution and sensitivity allow the detection of small chemical shift variations, which enables investigation of the supramolecular interaction between NaPF 6 and α‐cyclodextrin.

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