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Controlled Growth of Peptide Nanoarrays on Si/SiO x Substrates
Author(s) -
Zhou Xiaozhu,
Chen Yanhong,
Li Bing,
Lu Gang,
Boey Freddy Y. C.,
Ma Jan,
Zhang Hua
Publication year - 2008
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.200701267
Subject(s) - peptide , nanolithography , nanotechnology , substrate (aquarium) , nanostructure , materials science , polymerization , dendrimer , fabrication , self assembly , tryptophan , self assembling peptide , chemistry , chemical engineering , polymer chemistry , polymer , amino acid , nanofiber , geology , medicine , biochemistry , alternative medicine , oceanography , pathology , composite material , engineering
PAMAM dendrimer nanopatterns on Si/ SiO x substrates generated by dip‐pen nanolithography are used as anchoring scaffolds for the growth of peptides in situ by ring‐opening polymerization of tryptophan‐ N ‐carboxyanhydrides. This new method for the fabrication of peptide nanoarrays (see image) on a solid substrate is unique in that the growth of peptide nanostructures is controlled by the reaction time and the concentration of the tryptophan species.