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Fluorescent Core/Shell Nanoparticles for Specific Cell‐Nucleus Staining
Author(s) -
Yin Meizhen,
Shen Jie,
Gropeanu Radu,
Pflugfelder Gert O.,
Weil Tanja,
Müllen Klaus
Publication year - 2008
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.200701107
Subject(s) - fluorescence , nucleus , atom transfer radical polymerization , nanoparticle , core (optical fiber) , polymerization , shell (structure) , chemistry , water soluble , biophysics , solubility , nanotechnology , combinatorial chemistry , cell , polymer chemistry , photochemistry , materials science , polymer , biochemistry , organic chemistry , physics , biology , microbiology and biotechnology , optics , composite material
Water‐soluble fluorescent core/shell nanoparticles containing multiple ‐COOH groups are synthesized via atom‐transfer radical polymerization by applying perylenediimide derivatives as the template. This novel dye combines good water‐solubility and attractive optical properties. It specifically stains the cell nucleus by binding to positively charged nuclear proteins (see image).