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A SERS‐Active Nanocrystalline Pd Substrate and its Nanopatterning Leading to Biochip Fabrication
Author(s) -
Bhuvana Thiruvelu,
Kulkarni Giridhar U.
Publication year - 2008
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.200701075
Subject(s) - materials science , nanocrystalline material , nanotechnology , substrate (aquarium) , fabrication , biomolecule , raman scattering , electron beam lithography , nanocrystal , raman spectroscopy , biochip , resist , optics , medicine , oceanography , alternative medicine , physics , pathology , layer (electronics) , geology
Nanocrystalline metallic Pd films have been produced by thermolysis of Pd hexadecanethiolate deposited on a Si surface. The particle size was in the range of 50–60 nm based on electron and atomic force microscopy. The Pd surface produced was found to be surface‐enhanced Raman scattering (SERS) active with an enhancement factor of ≈10 5 . The electron‐resist behavior of Pd thiolate is exploited in conceptualizing a prototype chip with patterned Pd regions that are SERS active, called “SERS bits”, which host different biomolecules.