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Controlling the Self‐Assembly of a Filamentous Hyperthermophilic Chaperone by an Engineered Capping Protein
Author(s) -
Whitehead Timothy A.,
Meadows Adam L.,
Clark Douglas S.
Publication year - 2008
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.200700848
Subject(s) - template , protein filament , limiting , mutant , nanotechnology , chaperone (clinical) , thermophile , chemistry , biophysics , computational biology , computer science , materials science , biology , biochemistry , engineering , gene , medicine , pathology , mechanical engineering , enzyme
TERMinal filaments : Design of repeatable protein nanostructures is a limiting factor in the use of proteins as advanced materials templates. A capping protein of a new protein filament, γ PFD (see image), and a thermophilic extension resistant mutant (TERM) are constructed, control of overall length is demonstrated, and length distributions are quantitatively predicted.

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