Premium
Quantum‐Dot‐Based Electrochemical Immunoassay for High‐Throughput Screening of the Prostate‐Specific Antigen
Author(s) -
Wang Jun,
Liu Guodong,
Wu Hong,
Lin Yuehe
Publication year - 2008
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.200700459
Subject(s) - quantum dot , immunoassay , prostate specific antigen , throughput , biosensor , high throughput screening , electrochemistry , materials science , antigen , nanotechnology , chromatography , optoelectronics , prostate cancer , computer science , chemistry , electrode , cancer , antibody , telecommunications , immunology , medicine , biochemistry , wireless
Biosensing platform for immunoreactions: An electrochemical high‐throughput sensing platform for simple, sensitive detection of prostate‐specific serum antigen (PSA) based on quantum dot (QD) labels is demonstrated (see figure). The high sensitivity stems from the dual signal amplification via QD labels and preconcentration, allowing for detection of extremely low concentrations while using small sample volumes.