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Titania Nanotubes: A Novel Platform for Drug‐Eluting Coatings for Medical Implants?
Author(s) -
Popat Ketul C.,
Eltgroth Matthew,
LaTempa Thomas J.,
Grimes Craig A.,
Desai Tejal A.
Publication year - 2007
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.200700412
Subject(s) - materials science , anodizing , nanotechnology , nanotube , drug , kinetics , drug delivery , carbon nanotube , composite material , psychology , psychiatry , aluminium , physics , quantum mechanics
Nanotubes for drug release : Titania nanotubes (see image) fabricated by an easy anodization process can be used as drug‐eluting coatings for implantable devices. The release rate of the drugs is controlled by varying the amount of proteins loaded into the nanotubes. Moreover, by changing the nanotube diameter, wall thickness, and length, the release kinetics can be altered for each specific drug to achieve a sustained release.