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DNA‐Regulated Micro‐ and Nanoparticle Assembly
Author(s) -
Maye Mathew M.,
Nykypanchuk Dmytro,
van der Lelie Daniel,
Gang Oleg
Publication year - 2007
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.200700357
Subject(s) - dna , nanoparticle , nanotechnology , steric effects , kinetics , materials science , dna nanotechnology , self assembly , dna–dna hybridization , chemistry , stereochemistry , physics , biochemistry , quantum mechanics
A novel use of DNA as a platform to tailor interparticle attraction and repulsion in micro‐ and nanosystems (see figure) is described. The total interparticle energy is regulated by balancing attractive forces generated by complementary DNA hybridization with steric repulsion provided by noncomplementary DNA. This allows for the control of assembly kinetics, size, and structure of both DNA‐capped micro‐ and nanoparticles.