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Polymer‐Mediated Synthesis of Ferritin‐Encapsulated Inorganic Nanoparticles
Author(s) -
Li Mei,
Viravaidya Chulanapa,
Mann Stephen
Publication year - 2007
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.200700199
Subject(s) - biomineralization , nanoparticle , nucleation , methacrylic acid , template , polymer , superparamagnetism , ferritin , nanostructure , nanotechnology , materials science , precipitation , sponge , methacrylate , chemical engineering , chemistry , polymerization , biochemistry , organic chemistry , physics , magnetization , botany , quantum mechanics , meteorology , magnetic field , engineering , composite material , biology
Building only on the inside : Poly(methacrylic acid) mediated inhibition of bulk precipitation is used to direct the nucleation and growth of CaCO 3 , SrCO 3 , BaCO 3 , or calcium phosphate nanoparticles specifically within the empty cavity of the iron‐storage protein, apoferritin, to produce new types of biomimetic nanostructures (see image). The approach is facile and should be readily applicable to other capsid‐like biological templates, such as viroids, enzyme complexes, and chaperonins.