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Magnetic Force Microscopy of Superparamagnetic Nanoparticles
Author(s) -
Schreiber Sharon,
Savla Mayur,
Pelekhov Denis V.,
Iscru Daniel F.,
Selcu Camelia,
Hammel P. Chris,
Agarwal Gunjan
Publication year - 2008
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.200700116
Subject(s) - superparamagnetism , magnetic force microscope , materials science , nanoscopic scale , magnetic nanoparticles , nanotechnology , magnetic field , microscopy , nanoparticle , scanning probe microscopy , nuclear magnetic resonance , optics , magnetization , physics , quantum mechanics
The use of magnetic force microscopy (MFM) to detect probe–sample interactions from superparamagnetic nanoparticles in vitro in ambient atmospheric conditions is reported here. By using both magnetic and nonmagnetic probes in dynamic lift‐mode imaging and by controlling the direction and magnitude of the external magnetic field applied to the samples, it is possible to detect and identify the presence of superparamagnetic nanoparticles. The experimental results shown here are in agreement with the estimated sensitivity of the MFM technique. The potential and challenges for localizing nanoscale magnetic domains in biological samples is discussed.