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Direct Electronic Detection of Prostate‐Specific Antigen in Serum
Author(s) -
Briman Mikhail,
Artukovic Erika,
Zhang Li,
Chia David,
Goodglick Lee,
Gruner George
Publication year - 2007
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.200700079
Subject(s) - prostate specific antigen , biosensor , prostate cancer , carbon nanotube , antigen , capacitor , materials science , nanotechnology , medicine , chemistry , cancer , immunology , electrical engineering , engineering , voltage
Carbon‐nanotube network capacitors detect the presence of proteins directly from untreated serum. The devices are fabricated by a simple room‐temperature technique and the detection scheme follows the protocol for protein assays currently used in clinical research. Prostate specific antigen, a marker for prostate cancer, is detected at concentrations of 1–100 ng mL −1 (see graph) as proof of principle for the detection capability of these novel biosensors.