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Double‐Stranded RNA Polyinosinic–Polycytidylic Acid Immobilized onto γ‐Fe 2 O 3 Nanoparticles by Using a Multifunctional Polymeric Linker
Author(s) -
Shukoor Mohammed Ibrahim,
Natalio Filipe,
Ksenofontov Vadim,
Tahir Muhammad Nawaz,
Eberhardt Marc,
Theato Patrick,
Schröder Heinz C.,
Müller Werner E. G.,
Tremel Wolfgang
Publication year - 2007
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.200600664
Subject(s) - linker , phosphoramidate , nanoparticle , magnetic nanoparticles , surface modification , polymer , maghemite , nucleic acid , drug delivery , combinatorial chemistry , chemistry , materials science , nanotechnology , organic chemistry , biochemistry , computer science , operating system
Magnetic medicines : The immobilization of the abnormal nucleic acid polyinosinic–polycytidylic acid (poly(IC)) on γ‐Fe2O3 maghemite nanoparticles through the phosphoramidate route by using a multifunctional polymer is reported. This approach may open new possibilities for magnetic drug delivery applications. The image shows γ‐Fe2O3 nanoparticles after polymer functionalization.