Premium
Enzymatic Disassembly of DNA–Gold Nanostructures
Author(s) -
Kanaras Antonios G.,
Wang Zhenxin,
Brust Mathias,
Cosstick Richard,
Bates Andrew D.
Publication year - 2007
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.200600494
Subject(s) - dna , ecori , linker , nanotechnology , restriction enzyme , cleavage (geology) , nanostructure , enzyme , chemistry , nanoscopic scale , computational biology , computer science , combinatorial chemistry , biochemistry , materials science , biology , fracture (geology) , composite material , operating system
The efficient digestion of nanoparticle assemblies connected by DNA linkers is demonstrated using a number of complementary methods (enzymatic cleavage with Eco RI is shown in the scheme). The efficiency of digestion is dependent on the design of the DNA linker. The ability to manipulate DNA enzymatically is important in the development of hierarchical chemical methods of nanoscale assembly.