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Ultrasound‐Triggered Release from Multilayered Capsules
Author(s) -
De Geest Bruno G.,
Skirtach Andre G.,
Mamedov Arif A.,
Antipov Alexei A.,
Kotov Nicholas A.,
De Smedt Stefaan C.,
Sukhorukov Gleb B.
Publication year - 2007
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.200600441
Subject(s) - capsule , ultrasound , materials science , layer (electronics) , ultrasonic sensor , macromolecule , membrane , biomedical engineering , nanotechnology , chemistry , radiology , medicine , biochemistry , botany , biology
Sound effects : Multilayered capsules, such as that shown in the SEM image, are promising vehicles for the delivery of macromolecular drugs. Ultrasonic irradiation can be used to trigger the release of encapsulated species from capsules fabricated using layer‐by‐layer technology. Ultrasound affects the integrity of the capsule membrane, which leads to destruction of the entire capsule and release of the contents.