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Confined Diffusion in Ordered Nanoporous Alumina Membranes
Author(s) -
Hohlbein J.,
Steinhart M.,
SchieneFischer C.,
Benda A.,
Hof M.,
Hübner Christian G.
Publication year - 2007
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.200600398
Subject(s) - nanoporous , nanoscopic scale , materials science , diffusion , nanotechnology , fluorescence , membrane , molecule , nanopore , porosity , macromolecule , schematic , chemical engineering , chemistry , organic chemistry , optics , composite material , biochemistry , physics , engineering , electronic engineering , thermodynamics
Functionalized nanoporous alumina is applied in single‐molecule fluorescence detection in nanoscale confinement (see schematic image). The confinement leads to apparent 1D diffusion with up to 19‐fold prolonged diffusion times through the focus. Single‐molecule fluorescence in porous alumina is a promising tool for the study of dynamical processes in macromolecular systems and for highly parallel ultrasensitive analytical applications.