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Semisynthetic Biogenic Magnetosome Nanoparticles for the Detection of Proteins and Nucleic Acids
Author(s) -
Ceyhan Buelent,
Alhorn Petra,
Lang Claus,
Schüler Dirk,
Niemeyer Christof M.
Publication year - 2006
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.200600282
Subject(s) - magnetosome , nanoparticle , nucleic acid , oligonucleotide , iron oxide nanoparticles , magnetic nanoparticles , chemistry , colloidal gold , dna , nanotechnology , magnetite nanoparticles , nanobiotechnology , reagent , materials science , biophysics , biochemistry , magnetite , biology , organic chemistry , metallurgy
An attractive approach : Biogenic magnetic nanoparticles, so‐called magnetosomes, containing a magnetic iron oxide core enclosed in a protein–lipid membrane, were chemically functionalized with DNA oligonucleotides by using a modular coupling approach. The resulting nanoparticles were used for the assembly of heterostructures with DNA‐modified gold nanoparticles (see TEM image) and as reagents for protein detection.