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Fabrication of Particulate Reservoir‐Containing, Capsulelike, and Self‐Folding Polymer Microstructures for Drug Delivery
Author(s) -
Guan Jingjiao,
He Hongyan,
Lee L. James,
Hansford Derek J.
Publication year - 2007
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.200600240
Subject(s) - materials science , polymer , fabrication , particulates , nanotechnology , drug delivery , folding (dsp implementation) , molding (decorative) , composite material , mechanical engineering , chemistry , organic chemistry , medicine , alternative medicine , pathology , engineering
Particulate polymer microdevices are fabricated using protocols based on a transfer‐molding process that allows the controlled assembly of multiple materials to produce functional devices. Specifically, protocols for reservoir‐containing (see image; scale bar=100 μm), capsulelike, and self‐folding polymer microdevices are presented. The encapsulated materials are not exposed to high temperatures or caustic solutions, which is important in drug‐delivery applications.