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Efficient Proteolysis System: A Nanozeolite‐Derived Microreactor
Author(s) -
Zhang Yahong,
Liu Yun,
Kong Jilie,
Yang Pengyuan,
Tang Yi,
Liu Baohong
Publication year - 2006
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.200600138
Subject(s) - proteolysis , microreactor , microfluidics , nanotechnology , materials science , trypsin , bioreactor , chemistry , organic chemistry , enzyme , catalysis
When the chips are down : A stable zeolite nanocrystal matrix accommodating trypsin has been constructed on a microfluidic chip as a bioreactor to favor highly efficient proteolysis (see picture). The whole procedure is rapid and easily manipulated, thus providing a promising way to solve low‐efficiency digestion in advancing the development of proteomics. PMMA=poly(methyl methacrylate).