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Nanoscale Biosensors: Significant Advantages over Larger Devices?
Author(s) -
Gooding J. Justin
Publication year - 2006
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.200500477
Subject(s) - biosensor , nanoscopic scale , nanotechnology , materials science , nanowire , multiplexing , analyte , silicon nanowires , field effect transistor , transistor , chemistry , computer science , physics , chromatography , telecommunications , voltage , quantum mechanics
Nanoscale multiplexing biosensors : Biosensors fabricated using silicon‐nanowire‐based field‐effect transistors not only have high sensitivity but can be multiplexed so that a number of analytes have unique properties, exhibiting reversibility of immunobinding and insignificant levels of nonspecific binding. The excellent performance of these biosensors can be attributed partly to their nanoscale dimensions, where only a small number of binding events are being detected.