Premium
Visualization of Size‐Selective Protein Separations on Spherical Mesoporous Silicates
Author(s) -
Katiyar Amit,
Pinto Neville G.
Publication year - 2006
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.200500473
Subject(s) - mesoporous material , isothermal microcalorimetry , mesoporous silica , materials science , particle size , molecular sieve , chemical engineering , confocal laser scanning microscopy , particle (ecology) , scanning electron microscope , nanotechnology , chromatography , chemistry , biophysics , organic chemistry , adsorption , composite material , physics , oceanography , quantum mechanics , biology , geology , engineering , enthalpy , catalysis
Pores for effect : Spherical, mesoporous silica particles with pore sizes ranging from 28–127 Å and particle diameters of 5–10 μm were used to achieve size‐based separations of two proteins (see figure). This separation has been visualized using confocal scanning laser microscopy and confirmed with flow microcalorimetry. The results show that mesoporous silicates can be developed as molecular‐sieve media for protein separation.