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Transport of Semiconductor Nanocrystals by Kinesin Molecular Motors
Author(s) -
Muthukrishnan Gayatri,
Hutchins Benjamin M.,
Williams Mary Elizabeth,
Hancock William O.
Publication year - 2006
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.200500223
Subject(s) - kinesin , molecular motor , semiconductor , nanocrystal , nanotechnology , materials science , motor protein , optoelectronics , microtubule , biology , microbiology and biotechnology
Biotin‐functionalized quantum dots were synthesized and conjugated to kinesin molecular motors through a neutravidin bridging molecule (see figure). Quantum dot–kinesin complexes were visualized moving along immobilized microtubules by either total internal reflection fluorescence or epifluorescence microscopy. This study provides a new approach for long‐term biomotor imaging and establishes a model for biomotor‐driven nanoparticle transport and assembly.