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Synthesis of Gold Nanoparticles Using Multifunctional Peptides
Author(s) -
Slocik Joseph M.,
Stone Morley O.,
Naik Rajesh R.
Publication year - 2005
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.200500172
Subject(s) - colloidal gold , dispersity , nanotechnology , nanoparticle , domain (mathematical analysis) , peptide , combinatorial chemistry , aqueous medium , computer science , chemistry , materials science , aqueous solution , biochemistry , organic chemistry , mathematics , mathematical analysis
A simple, one‐pot process for synthesizing monodisperse gold nanoparticles in aqueous solution using multifunctional peptides is reported (see Figure). The multifunctional peptide contains a gold synthesizing/binding domain and a biomolecular recognition domain. The gold binding domain reduces choloroaurate ions and coats the gold nanoparticles while the biomolecular recognition domain can be recognized by specific antibodies.